| Purity: | > 99%HPLC |
|---|---|
| Usage: | Research Use |
| Total Aerobic Microbial Count: | < 10 Cfu/G |
| Storage Condition: | 2c - 8c, Well-Closed Containers |
| Color: | White |
| Transport Package: | Vials/Tubes/Bottles |
| Samples: |
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| Customization: |
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Selank is a synthetic peptide made by combining the sequence of the tuftsin peptide with another sequence that enhances its molecular stability. Tuftsin occurs naturally [i] in the body and is responsible for keeping the immune system strong, but selank works more effectively.
According to research, selank functions by stabilizing enkephalins in the blood. Enkephalins are peptides produced naturally in the body that work to counteract the stress response.
Some cell studies [ii] suggest that the peptide selank may connect itself to GABA receptors which causes sedative effects. In a study on mice, those treated with a selank dose displayed increased activity in the inhibitory neurons, resulting in less brain activity - otherwise known as a sedative effect.
Further research implies that an increase in BDNF can improve memory and learning and strengthen overall cognitive functions.
There is also evidence to suggest that TP7 can influence the levels of the neurotransmitter's dopamine, norepinephrine, and serotonin - all of which play a role in focus, happiness, and motivation.
On the other hand, one animal study found that selank peptide effects included increasing norepinephrine but lessened serotonin and dopamine levels. This just goes to show that its functions remain somewhat unclear and that further research is needed.
Let's take a more in-depth look at the benefits, backed up animal studies and clinical trials.
Semax is a Russian experimental drug used for the prevention and treatment of cognitive and circulatory disorders. It is a synthetic peptide drug that has not been approved by the FDA for medical purposes but is considered a potent treatment for cognitive issues.
The peptide semax upsurges brain-derived neurotrophic factor (BDNF) levels which help stimulate and control the birth of new neurons in the brain, as tests showed.
BDNF plays a role in neuroplasticity, which enables nerve cells in the brain to adapt to new situations. Essentially, it helps to aid the survival of existing neurons and promotes the growth and creation of new neurons and synapses.
Research has shown, Semax also reduces the breakdown of enkephalins, the chemicals involved in eliminating pain, inflammation, and cancer cell growth. Enkephalins also play a role in memory, emotional behaviour, learning, and pain.
Animals need balanced enkephalin levels in order to maintain healthy brain function. Semax treatment promotes the wellbeing of these chemicals to ensure the health of the brain.
There are a number of benefits of Semax peptide. Here are some of its potential benefits, as discovered by scientists, as researches showed:
According to studies, semax health benefits also include improved blood circulation and oxidative damage protection as research in animals has shown. Let's take a closer look at Semax effects on health.
GENERIC PEPTIDES (GMP)
| # | Product | Sequence | Therapeutic Area | Form | Unit Size |
| 4109712 | Semaglutide CAS No.: 910463-68-2 |
H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH | Type II diabetes mellitus Obesity |
Lyophilized powder | 2 mg/vial 5 mg/vial 10 mg/vial 15 mg/vial 20 mg/vial 1 g/tube |
| 4109713 | Tirzepatide CAS No.: 2023788-19-2 |
H-Tyr-{Aib}-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-{Aib}-Leu-Asp-Lys-Ile-Ala-Gln-{diacid-gamma-Glu-(AEEA)2-Lys}-Ala-Phe-Val-Gln-Trp-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 | Type II diabetes mellitus Obesity |
Lyophilized powder | 10 mg/vial 15 mg/vial 20 mg/vial 30 mg/vial 60 mg/vial 1 g/tube |
| 4109714 | Cagrilintide CAS No.: 1415456-99-3 |
{Eicosanedioic acid-γ-Glu}-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Glu-Phe-Leu-Arg-His-Ser-Ser-Asn-Asn-Phe-Gly-Pro-Ile-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Pro-NH2 | Type II diabetes mellitus Obesity |
Lyophilized powder | 5 mg/vial 10 mg/vial 1 g/tube |
| 4109715 | CagriSema | Blend | Type II diabetes mellitus Obesity |
Lyophilized powder | 5 mg/vial 10 mg/vial 20 mg/vial 1 g/tube |
| 4109716 | Retatrutide CAS No. 2381089-83-2 |
Tyr-{Aib}-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-{α-Me-Leu}-Leu-Asp-Lys-{diacid-C20-gamma-Glu-(AEEA)-Lys}-Ala-Gln-{Aib}-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 | Treatment of type 2 diabetes Treatment of obesity |
Lyophilized powder | 8 mg 10 mg 12 mg 15 mg 1 g/tube |
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cGMP peptides Manufacturing
Zhaobo Bio acquired early mastery of development and manufacturing of peptides, the short chain amino acids linked by peptide bonds that have enabled new generations of small molecule drugs that closely mimic the body's natural pathways.
Now Zhaobo Bio possesses first-class capabilities to manufacture peptides at industrial scale and in full compliance with the strictest Good Manufacturing Practice (cGMP) standards.
Upstream peptide synthesis
Zhaobo Bio production plants are endowed with state-of-the-art equipment for solvent supply, peptide synthesis, purification and isolation of active ingredients and intermediates. All equipment and containment is GMP qualified and cleaning validated. Overlapping capacities and sizes of different equipment trains facilitate a smooth scale-up for increases in demand within the product life cycle.
Downstream purification and isolation of peptides
Zhaobo Bio is committed to the systematic expansion and modernization of its purification equipment in order to ensure the efficient production of ever-increasing amounts of bulk peptide pharmaceuticals.
It uses sophisticated methods for large scale purification campaigns such as preparative high performance liquid chromatography (HPLC), ion exchange (IEX), size-exclusion chromatography (SEC), and ultra-filtration (UF/TFF). The equipment in place permits highly efficient or even continuous manufacturing of extremely pure products up to multi-kg quantities per lot.
For preparative HPLC, dynamic axial compression (DAC) stainless steel columns of up to 60 cm diameter both in batch and continuous mode are packed with the appropriate high performance silica separation phase. For low-pressure chromatography columns up to 80 cm diameter are available. Solvent delivery is ensured from eluent tank farms and containers.
The control of microbiological contamination is a prerequisite for API manufacturing. Class D (ISO 8) and C (ISO 7) clean rooms are supplied via HEPA-filtered, temperature and humidity controlled air, down-flow booths are used for minimizing microbial contamination and protecting operators. Highly active pharmaceutical ingredients are handled in integrated safety workbenches or flexible isolators reaching OEB level 4 (1-10 µg/m3).
Predefined physicochemical properties of the API can only be achieved by a carefully controlled isolation process. Besides precipitation and crystallization, lyophilization of intermediates and final API is a standard unit operation. LaixingPharma have multiple lyophilizers in different sizes (up to 300 liters) located in clean rooms.
ZhaoboBio's Peptide Plant also manufactures and offers a range of specialized services for the cGMP Small Molecules.
Small molecule production capabilities include: process development, chiral synthesis, heterocyclic chemistry, metal-catalyzed reactions, hydrogenations, oxidations and reductions using various reagents, enzymatic reactions, and high pressure reactions.
FAQ
1. How to preserve peptides after receiving them?
Peptides in the form of lyophilized powder can be transported at room temperature by vacuum packaging, while polypeptides in the dissolved state need to be refrigerated at 2°C - 8°C. For long-term storage, peptides should be stored in the form of lyophilized powder stored at -20°C or -80°C in a sealed container with desiccant, which can avoid the degradation of peptides to the greatest extent.
5. Will I have any side effects after using peptide?
If you just begin to use, it is better to follow doctor's prescription. And if there is no allergy or any uncomfortable symptom, you can continue to use but take it in a suitable dosage. A few people will have slight allergy reaction, but after your body get used to it, the allergy will be disappear and back to normal.
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