| Customization: | Available |
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| CAS No.: | / |
| Formula: | C26h36n6o9 |
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Amino Acid Sequence: Lys-Glu-Asp-Trp (KEDW)
Molecular Formula: C26H36N609
Molecular Weight: 576.25 g/mol
PubChem CID: 68452887
Synonyms: SCHEMBL5491754
Pancragen is a naturally occurring tetrapeptide bioregulator that has primary effects on the pancreas. Pancragen research has shown it to help control blood sugar, improve endocrine function of the pancreas, regulate melatonin expression, and reduce the incidence and magnitude of metabolic syndrome. It has been researched and is of interest in the treatment of both diabetes and the metabolic effects of aging. Pancragen can be thought of as an anti-aging peptide for the pancreas.
Our Advantages: High purity, Wholesale price, large stock, Stealth Shipping, 100% Delivery Guarantee
Upstream peptide synthesis
Zhaobo Bio production plants are endowed with state-of-the-art equipment for solvent supply, peptide synthesis, purification and isolation of active ingredients and intermediates. All equipment and containment is GMP qualified and cleaning validated. Overlapping capacities and sizes of different equipment trains facilitate a smooth scale-up for increases in demand within the product life cycle.
Downstream purification and isolation of peptides
Zhaobo Bio is committed to the systematic expansion and modernization of its purification equipment in order to ensure the efficient production of ever-increasing amounts of bulk peptide pharmaceuticals.
It uses sophisticated methods for large scale purification campaigns such as preparative high performance liquid chromatography (HPLC), ion exchange (IEX), size-exclusion chromatography (SEC), and ultra-filtration (UF/TFF). The equipment in place permits highly efficient or even continuous manufacturing of extremely pure products up to multi-kg quantities per lot.
For preparative HPLC, dynamic axial compression (DAC) stainless steel columns of up to 60 cm diameter both in batch and continuous mode are packed with the appropriate high performance silica separation phase. For low-pressure chromatography columns up to 80 cm diameter are available. Solvent delivery is ensured from eluent tank farms and containers.
The control of microbiological contamination is a prerequisite for API manufacturing. Class D (ISO 8) and C (ISO 7) clean rooms are supplied via HEPA-filtered, temperature and humidity controlled air, down-flow booths are used for minimizing microbial contamination and protecting operators. Highly active pharmaceutical ingredients are handled in integrated safety workbenches or flexible isolators reaching OEB level 4 (1-10 µg/m3).
Predefined physicochemical properties of the API can only be achieved by a carefully controlled isolation process. Besides precipitation and crystallization, lyophilization of intermediates and final API is a standard unit operation. LaixingPharma have multiple lyophilizers in different sizes (up to 300 liters) located in clean room
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