Peptide Purity: | >99% |
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Name: | Kisspeptin-10 |
CAS Number: | 374675-21-5 |
Molecular Formula: | C63h83n17o14 |
Shelf Life: | 2 Years |
Stock: | Yes |
Samples: |
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Customization: |
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Kisspeptin 10 (human) Basic information |
Product Name: | Kisspeptin 10 (human) |
Synonyms: | MALIGNANT MELANOMA METASTASIS-SUPPRESSOR KISS-1 (112-121) (HUMAN);METASTIN (HUMAN, 45-54);METASTIN (45-54);METASTIN (45-54) AMIDE, HUMAN;METASTIN (45-54), HUMAN;KISSPEPTIN-13 (4-13) (HUMAN);KISS-1 GENE PRODUCT (HUMAN, 112-121 AMIDE);TYR-ASN-TRP-ASN-SER-PHE-GLY-LEU-ARG-PHE-NH2 |
CAS: | 374675-21-5 |
MF: | C63H83N17O14 |
MW: | 1302.44 |
EINECS: | |
Product Categories: | Peptide Receptors |
Mol File: | 374675-21-5.mol |
Kisspeptin 10 (human) Chemical Properties |
density | 1.46±0.1 g/cm3(Predicted) |
storage temp. | -20°C |
solubility | DMF: 15 mg/ml; DMSO: 15 mg/ml; DMSO:PBS(pH 7.2) (1:2): 0.33 mg/ml |
form | A crystalline solid |
pka | 9.96±0.15(Predicted) |
Water Solubility | Soluble in water at 1mg/ml |
Kisspeptin 10 (human) Usage And Synthesis |
Description | Kisspeptin-10, also called Metastin (45-54), is a 10 amino acid peptide that corresponds to the bioactive C-terminal 45-54 amino acids of metastin, a metastasis suppressor gene product. It acts as a potent agonist of GPR54 (OT7T175, AXOR12), with approximately 8-fold higher binding affinity than metastin (Ki values of 0.042 and 0.34 nM, respectively, for displacement of metastin (40-54)). Metastin (45-54) induces calcium mobilization in GPR54-transfected cells (EC50 = 0.18-1.1 nM). It inhibits the migration of GPR54-transfected CHO cells at concentrations of 10-100 nM, equaling the potency of full length metastin. |
Uses | Kisspeptin 10 (human) is a powerful and specific activator for AXOR12 and hOT7T175 receptors. The Kisspeptin 10 (human) amide has been utilized in studies involving progesterone release from MA-10 cells and in experiments to induce gonadal differentiation in clownfish. |
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ZB Bio has a long-standing track record in with successful registrations of highly purified synthetic peptide drugs of the glucagon family. Our regulatory intelligence keeps track of important changes in the relevant legislation. This enables us to be a leading global innovator in the field of glucagon and glucagon-like synthetic peptide drugs. Our services have been optimized to shorten timelines and of reduce complexity for our clients.
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