| Customization: | Available |
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| CAS No.: | / |
| Formula: | C11h17n3o8 |
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Chonluten is a research product that has gained attention in the scientific community for its potential therapeutic properties. It is a peptide derived from natural sources and has been extensively studied in non-human research models. Chonluten is known for its unique composition, which includes bioactive peptides and amino acids that have shown promising effects on various biological processes. The main component of Chonluten is chondroitin sulfate, a molecule found in connective tissues such as cartilage and bone.
Chondroitin sulfate has been widely studied for its potential benefits in promoting joint health and reducing inflammation. In addition to chondroitin sulfate, Chonluten contains other bioactive peptides that contribute to its overall therapeutic effects. Studies have shown that Chonluten can modulate immune responses, improve wound healing, and enhance tissue regeneration.
- Joint Health: Chonluten has been extensively studied for its potential effects on joint health. Research suggests that it may help reduce inflammation and support cartilage integrity, making it a valuable candidate for studying conditions such as osteoarthritis.
- Immune Modulation: Chonluten has shown immunomodulatory properties, meaning it can modulate immune responses. This makes it an interesting subject for research related to autoimmune diseases or conditions characterized by immune dysregulation.
- Wound Healing: Studies have indicated that Chonluten can enhance wound healing by promoting tissue regeneration and reducing inflammation at the site of injury. This makes it a valuable area of investigation in the field of wound care.
- Neuroprotection: Preliminary research suggests that Chonluten may have neuroprotective properties, potentially offering benefits in neurological disorders or conditions involving cognitive decline.
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Upstream peptide synthesis
Zhaobo Bio production plants are endowed with state-of-the-art equipment for solvent supply, peptide synthesis, purification and isolation of active ingredients and intermediates. All equipment and containment is GMP qualified and cleaning validated. Overlapping capacities and sizes of different equipment trains facilitate a smooth scale-up for increases in demand within the product life cycle.
Downstream purification and isolation of peptides
Zhaobo Bio is committed to the systematic expansion and modernization of its purification equipment in order to ensure the efficient production of ever-increasing amounts of bulk peptide pharmaceuticals.
It uses sophisticated methods for large scale purification campaigns such as preparative high performance liquid chromatography (HPLC), ion exchange (IEX), size-exclusion chromatography (SEC), and ultra-filtration (UF/TFF). The equipment in place permits highly efficient or even continuous manufacturing of extremely pure products up to multi-kg quantities per lot.
For preparative HPLC, dynamic axial compression (DAC) stainless steel columns of up to 60 cm diameter both in batch and continuous mode are packed with the appropriate high performance silica separation phase. For low-pressure chromatography columns up to 80 cm diameter are available. Solvent delivery is ensured from eluent tank farms and containers.
The control of microbiological contamination is a prerequisite for API manufacturing. Class D (ISO 8) and C (ISO 7) clean rooms are supplied via HEPA-filtered, temperature and humidity controlled air, down-flow booths are used for minimizing microbial contamination and protecting operators. Highly active pharmaceutical ingredients are handled in integrated safety workbenches or flexible isolators reaching OEB level 4 (1-10 µg/m3).
Predefined physicochemical properties of the API can only be achieved by a carefully controlled isolation process. Besides precipitation and crystallization, lyophilization of intermediates and final API is a standard unit operation. LaixingPharma have multiple lyophilizers in different sizes (up to 300 liters) located in clean room
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