| Customization: | Available |
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| Purity: | > 99%HPLC |
| Molecular Weight: | 430.17 G/Mol |
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Cortagen is a research peptide that has gained significant attention in the scientific community for its potential applications in non-human research. It is composed of a sequence of amino acids that mimic certain natural peptides found in the body. This synthetic peptide is typically used in laboratory settings to investigate its effects on various biological processes and pathways. The primary purpose of Cortagen in non-human research is to study its impact on specific physiological systems or functions.
1. Promotion: Studies have suggested that Cortagen may enhance and protein synthesis, making it a valuable tool for studying muscle development and potential interventions for muscle-related disorders.
2. Tissue Repair Enhancement: Cortagen has been shown to modulate inflammatory processes involved in tissue repair. This property makes it relevant for investigating potential therapeutic strategies for promoting tissue regeneration or accelerating wound healing.
3. Cognitive Function Improvement: Preliminary research suggests that Cortagen may have cognitive-enhancing effects, potentially influencing memory formation or learning processes in non-human subjects. This opens up avenues for exploring its potential applications in neurobiology and neuroscience research.
4. Versatile Research Applications: Due to its diverse effects on various physiological systems, Cortagen can be used to investigate a wide range of research topics. These may include studies on metabolism, aging, cardiovascular health, or even neurodegenerative diseases.
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Upstream peptide synthesis
Zhaobo Bio production plants are endowed with state-of-the-art equipment for solvent supply, peptide synthesis, purification and isolation of active ingredients and intermediates. All equipment and containment is GMP qualified and cleaning validated. Overlapping capacities and sizes of different equipment trains facilitate a smooth scale-up for increases in demand within the product life cycle.
Downstream purification and isolation of peptides
Zhaobo Bio is committed to the systematic expansion and modernization of its purification equipment in order to ensure the efficient production of ever-increasing amounts of bulk peptide pharmaceuticals.
It uses sophisticated methods for large scale purification campaigns such as preparative high performance liquid chromatography (HPLC), ion exchange (IEX), size-exclusion chromatography (SEC), and ultra-filtration (UF/TFF). The equipment in place permits highly efficient or even continuous manufacturing of extremely pure products up to multi-kg quantities per lot.
For preparative HPLC, dynamic axial compression (DAC) stainless steel columns of up to 60 cm diameter both in batch and continuous mode are packed with the appropriate high performance silica separation phase. For low-pressure chromatography columns up to 80 cm diameter are available. Solvent delivery is ensured from eluent tank farms and containers.
The control of microbiological contamination is a prerequisite for API manufacturing. Class D (ISO 8) and C (ISO 7) clean rooms are supplied via HEPA-filtered, temperature and humidity controlled air, down-flow booths are used for minimizing microbial contamination and protecting operators. Highly active pharmaceutical ingredients are handled in integrated safety workbenches or flexible isolators reaching OEB level 4 (1-10 µg/m3).
Predefined physicochemical properties of the API can only be achieved by a carefully controlled isolation process. Besides precipitation and crystallization, lyophilization of intermediates and final API is a standard unit operation. LaixingPharma have multiple lyophilizers in different sizes (up to 300 liters) located in clean room
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