| Customization: | Available |
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| CAS No.: | 80714-61-0 |
| Formula: | C37h51n9o10s |
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Semax is a peptide best known for its nootropic, neuroprotective, and neurogenic/neurorestorative properties. It was developed based on the molecular structure of adrenocorticotropic hormone (ACTH). Preliminary research in cells, animal and small-scale human trials show potential benefits and uses of Semax.
In the U.S. and around the world, Semax is the basis for a number of drugs that are used in clinical practice for the treatment of CNS diseases (ischemic brain stroke, dys-circulatory encephalopathy, optic nerve atrophy, etc.) and to enhance adaptability under extreme conditions in healthy persons.
Some of the benefits of Semax may include:
Semax increases brain-derived neurotrophic factor (BDNF) levels. BDNF is among the most active neurotrophins, which are chemicals that help to stimulate and control neurogenesis, the birth of new neurons in the brain.
BDNF has been shown to play a role in neuroplasticity, which allows nerve cells in the brain to compensate for injury and adapt to new situations or changes in the environment. Basically, BDNF helps to support the survival of existing neurons and encourages the growth, regeneration, and creation of new neurons and synapses.
Semax also helps reduce the breakdown of enkephalins. Enkephalins are mainly involved in decreasing pain, reducing inflammation, preventing cancer cell growth, and increasing immune cell activity. They also play a role in memory, learning, emotional behavior, and pain. Balanced enkephalins levels are needed to maintain normal brain function. These early findings have led some researchers to suggest that Semax may have some potential as a pain reliever, although much more research would be needed to confirm these preliminary cell-based findings.
Based on what Semax can do for brain function and health, its capabilities as a treatment option are continually being developed.
| Items | Specifications |
| Business Type | We are a manufacturer of GMP peptide and provide OEM service. The lid also can be customized |
| Filling amount | The filling amount is 2-5mg extra per bottle. |
| Purity | The purity is above 99% |
| Price | Competitive price |
| Delivery time | The delivery time is stable and short. If you pay before 12 a.m,the goods can be shipped on the same day. |
| Shipping risk | If the package was lost we will resend the goods to you,so you won't suffer a loss if you buy it. |
Zhaobo Bio acquired early mastery of development and manufacturing of peptides, the short chain amino acids linked by peptide bonds that have enabled new generations of small molecule drugs that closely mimic the body's natural pathways.
Now Zhaobo Bio possesses first-class capabilities to manufacture peptides at industrial scale and in full compliance with the strictest Good Manufacturing Practice (GMP) standards.
Upstream peptide synthesis
Zhaobo Bio production plants are endowed with state-of-the-art equipment for solvent supply, peptide synthesis, purification and isolation of active ingredients and intermediates. All equipment and containment is GMP qualified and cleaning validated. Overlapping capacities and sizes of different equipment trains facilitate a smooth scale-up for increases in demand within the product life cycle.
Downstream purification and isolation of peptides
Zhaobo Bio is committed to the systematic expansion and modernization of its purification equipment in order to ensure the efficient production of ever-increasing amounts of bulk peptide pharmaceuticals.
It uses sophisticated methods for large scale purification campaigns such as preparative high performance liquid chromatography (HPLC), ion exchange (IEX), size-exclusion chromatography (SEC), and ultra-filtration (UF/TFF). The equipment in place permits highly efficient or even continuous manufacturing of extremely pure products up to multi-kg quantities per lot.
For preparative HPLC, dynamic axial compression (DAC) stainless steel columns of up to 60 cm diameter both in batch and continuous mode are packed with the appropriate high performance silica separation phase. For low-pressure chromatography columns up to 80 cm diameter are available. Solvent delivery is ensured from eluent tank farms and containers.
The control of microbiological contamination is a prerequisite for API manufacturing. Class D (ISO 8) and C (ISO 7) clean rooms are supplied via HEPA-filtered, temperature and humidity controlled air, down-flow booths are used for minimizing microbial contamination and protecting operators. Highly active pharmaceutical ingredients are handled in integrated safety workbenches or flexible isolators reaching OEB level 4 (1-10 µg/m3).
Predefined physicochemical properties of the API can only be achieved by a carefully controlled isolation process. Besides precipitation and crystallization, lyophilization of intermediates and final API is a standard unit operation. LaixingPharma have multiple lyophilizers in different sizes (up to 300 liters) located in clean rooms.
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