Support Customized Dose Sema Cartridge Vial with Pen for Injection

• Customization: Available
• Long-Term Storage: 2ºC- 8ºC, Well-Closed Containers
• Purity: >99%
• Total Combined Yeasts and Moulds Count: < 10 Cfu/G
• Total Aerobic Microbial Count: < 10 Cfu/G
• Appearance: Powder
• Color: White
• Transport Package: Box/Kit/Bag
• Specification: 10mg/15mg/20mg/30mg/40mg/Customize
• Trademark: GMP
• Origin: China
• Production Capacity: 100000 Vials Per Month

Product Description

 

Product Description

PRODUCT	Sema
SEQUENCE	H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH
FIELDS OF APPLICATION	Treatment of type II diabetes mellitus Treatment of obesity
ACTIVE SUBSTANCE	The peptide API Sema acts in the same way as GLP-1, the hormone produced in the gut. It helps increase the amount of insuli released by the pancreas in response to consumed food. Sema allows patients with type 2 diabetes to control their blood sugar levels better.
MOLECULAR FORMULA	C187H291N45O59
RELATIVE MOLECULAR MASS	4113.64 g/mol
PURITY	>99% HPLC
LONG-TERM STORAGE	-20 ± 5°C

Sema is an antidiabetic medication used for the treatment of tyoe 2 diabetes and an anti-obesity medication used for long-term weight management.It is a peptide similar to the hormone glucagon-like peptide-1(GLP-1),modified with a side chain.It can be administered by subcutaneous injection or taken orally.

Product Function:

• Helps slow food leaving your stomach
• Helps prevent your liver from making too much sugar
• Helps the pancreas produce more insul when your blood sugar levels are high
• Can help control blood glucose
• Can reduce hyperglycemia, especially after meals
• Can reduce fasting insul and fasting glucose
• Can reduce hemoglobin A1c
• Can decrease appetite and caloric intake, while inhibiting weight gain
• Has been shown to lower triglyceride levels and oxidative stress from high LDL
• Has been shown to help induce weight loss in obese patients with higher dosing
• Helps decrease leptin and increase leptin sensitivity
• Can increase the conversion of white fat to brown fat

Tests		Specifications	Results
Characters	Appearance	White to almost white loose powder	White loose powder
	Solubility	Soluble in water	Complies
Identifications	HPLC	The retention time of the major peak in the chromatogram of the test solution corresponds to that in the chromatogram of the Reference Solution, as obtained in the Assay	Complies
	MALDI-MS	4813.5±1.0 Da	4812.6 Da
Amino acid analysis		Ser: 4.0-6.0	4.6
		Asp: 1.6-2.4	1.6
		Thr: 1.6-2.4	1.8
		Pro: 3.2-4.8	4.1
		Tyr: 1.6-2.4	2.1
		Leu: 1.6-2.4	1.9
		Gly: 3.2-4.8	4.0
		Glu: 3.2-4.8	3.8
		Ala: 3.2-4.8	3.9
		Lys: 1.6-2.4	1.9
		Ile: 2.4-3.6	3.0
		Phe: 1.6-2.4	2.2
Peptide Purity (HPLC)		≥ 80%	93.6%
Related Substances	Impurities (HPLC)	Any unspecified impurity  ≤ 0.10%	0.06%
		Toal impurities ≤ 0.50%	0.12%
Oligomer		≤ 3.0%	0.27%
Water content (KF)		≤ 8.0%	4.63%
Sodium ion		Report	1.1%
Residual solvents (GC)		Acetonitril-e ≤ 410 ppm	246 ppm
Bacterial Endotoxins		≤ 10 EU/mg	Complies
Microbiology	Total aerobic microbial count	≤ 100 CFU/g	< 10 CFU/g
	Total combined yeasts and moulds count	≤ 100 CFU/g	< 10 CFU/g
	Escherichia coli count	Absent in 1g	Complies
Assay	Calculated as C18H14F4N2O4S on dried substance	98.0% - 102.0%	99.8%

 

Storage condition:	2°C - 8°C, well-closed containers, protected from light.
Remarks:	This batch of product COMPLIES with the prescribed standards.
Analysed on:	18.09.2023

Zhaobo Bio acquired early mastery of development and manufacturing of peptides, the short chain amino acids linked by peptide bonds that have enabled new generations of small molecule drugs that closely mimic the body's natural pathways.
Now Zhaobo Bio possesses first-class capabilities to manufacture peptides at industrial scale and in full compliance with the strictest Good Manufacturing Practice (cGMP) standards.Upstream peptide synthesis.
 

FAQ

1. How to preserve peptides after receiving them?
Peptides in the form of lyophilized powder can be transported at room temperature by vacuum packaging, while polypeptides in the dissolved state need to be refrigerated at 2°C - 8°C. For long-term storage, peptides should be stored in the form of lyophilized powder stored at -20°C or -80°C in a sealed container with desiccant, which can avoid the degradation of peptides to the greatest extent.
 

2. What is your lead time and shipping method?
Customized items are negotiable. 1-3 working day after payment arranges the shipping. Parcels shipping by sea, by air, or by express (EMS, UPS, DHL, TNT, FEDEX, etc).

 

3. Is the shipping 100% Guarantee?
Yes, we offer 100% Shipping Guarantee. If any seized parcel we will do resending. 

4. Will I have any side effects after using peptide?
If you just begin to use, it is better to follow doctor's prescription. And if there is no allergy or any uncomfortable symptom, you can continue to use but take it in a suitable dosage. A few people will have slight allergy reaction, but after your body get used to it, the allergy will be disappear and back to normal.

Welcome to be our distinguished customer, please do not hesitate to contact us!

#	Product	Sequence	Therapeutic Area	Form	Unit Size
4109712	Sema	H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH	Type II diabetes mellitus Obesity	Lyophilized powder	2 mg/vial 5 mg/vial 10 mg/vial 15 mg/vial 20 mg/vial 1 g/tube
4109713	Tirz	H-Tyr-{Aib}-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-{Aib}-Leu-Asp-Lys-Ile-Ala-Gln-{diacid-gamma-Glu-(AEEA)2-Lys}-Ala-Phe-Val-Gln-Trp-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2	Type II diabetes mellitus Obesity	Lyophilized powder	10 mg/vial 15 mg/vial 20 mg/vial 30 mg/vial 60 mg/vial 1 g/tube
4109714	Cagril	{Eicosanedioic acid-γ-Glu}-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Glu-Phe-Leu-Arg-His-Ser-Ser-Asn-Asn-Phe-Gly-Pro-Ile-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Pro-NH2	Type II diabetes mellitus Obesity	Lyophilized powder	5 mg/vial 10 mg/vial 1 g/tube
4109715	CagriSema	Blend	Type II diabetes mellitus Obesity	Lyophilized powder	5 mg/vial 10 mg/vial 20 mg/vial 1 g/tube
4109716	Reta	Tyr-{Aib}-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-{α-Me-Leu}-Leu-Asp-Lys-{diacid-C20-gamma-Glu-(AEEA)-Lys}-Ala-Gln-{Aib}-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2	Treatment of type 2 diabetes Treatment of obesity	Lyophilized powder	8 mg 10 mg 12 mg 15 mg 1 g/tube