Weight Loss Zepbound GLP-1 Semaglutide CAS 910463-68-2 Tirzepatide 2023788-19-2 Retatrutide 2381089-83-2 99% 5mg 10mg 15mg Vial Peptide

• Peptide Purity: >99%
• CAS Number: 910463-68-2
• Molecular Formula: C187h291n45o59
• Molecular Weight: 4113.57754
• Storage Condition: -20°c
• Shelf Life: 2 Years
• Model NO.: 910463-68-2
• Stock: Yes
• Delivery Time: Within 24 Hours After Payment
• Arrival Time: Around 12 Days
• Grade: Medical Grade
• Appearance: White Powder
• Transport Package: Vials/Tube
• Specification: 5mg, 10mg, 15mg, 1g
• Trademark: ZB
• Origin: China
• Production Capacity: 1-5kgs Per Month

Product Description

Product Description

GLP-1 Wholesale.
Semaglutide, Tirzepatide, Retatrutide, NAD, GHK-CU, Melanotan, Polypeptide  
5mg 10mg 15mg 20mg 30mg 1g
 
Our Advantages: High purity, Wholesale price, large stock, Stealth Shipping, 100% Delivery Guarantee

Common Name	Semaglutide acetate salt
CAS Number	910463-68-2	Molecular Weight	4113.57754
Density	N/A	Boiling Point	N/A
Molecular Formula	C187H291N45O59	Melting Point	N/A
MSDS	N/A	Flash Point	N/A

Semaglutide is a lipopeptide with a linear sequence of 31 amino acids. Like human Glucagon-like peptide-1 (GLP-1), it is used in combination with diet and exercise in the therapy of type 2 diabetes mellitus. It works as an anti-obesity agent, a neuroprotective agent, and an appetite depressant.
Semaglutide can be commercialized as a synthetic generic product after approval of an abbreviated new drug application (ANDA) or comparable applications with other regulatory authorities. The length and modifications make technical excellence and regulatory expertise a prerequisite for efficient filing and fast approval. High material quality and yield, robust processes including secure supply and innovative approaches at high-tech facilities will enable our customers to achieve their business goals

CERTIFICATE OF ANALYSIS

Product Name	Semaglutide	Sample Source		Workshop 106
Batch Number	LX106S2305107	Packing Size		131.03g/bag, 401.6g/bag, 477.57g/bag
Quantity	1010.2g	Manufacturing Date		Apr-10-2023
Number of Packages	3	Retest Date		Apr-09-2025
Sample Date	Apr-28-2023	Report Date		May-08-2023
Testing Reference	QC-03-1003-02, QC-02-1595-03
TEST ITEM	SPECIFICATION		TEST RESULT
Appearance	White or almost white loose powder		white loose powder
Solubility	Freely soluble in water, soluble in DMF at 1 mg/mL, 30 mg/mL in DMSO, 0.2 mg/ml in a 1:4 solution of DMSO:PBS		conforms
Identification (MS)	4111.12±0.5Da		4111.15
Identification (HPLC)	Examine the chromatograms obtained in the assay. The principal peak in the chromatogram obtained with the test solution is similar in retention time and size to the principal peak in the chromatogram obtained with reference solution.		conforms
Specific Optical Rotation [α]20D (anhydrous substance)	-6.0° to -16.0°		-10.3°
Purity (HPLC)	NLT 98.0%		99.47%
Water Content	NMT 8.0%		3.9%
pH	7.0 to 9.0		7.9
Solution Clarity and Color	Clear and colorless		conforms
Acid Group Ions	Trifluoroacetate ion NMT 0.1%		N.D.
	Phosphate ion NMT 0.1%		N.D.
	Chloride ion NMT 0.1%		0.003%
	Acetate ion NMT 0.1%		N.D.
Sodium Ion	NMT 4.0%		2.1%
Related Substances I	SPEC054-Z18 NMT 0.50%		N.D.
	SPEC054-Z20 NMT 0.30%		0.03%
	SPEC054-Z21 NMT 0.50%		N.D.
	SPEC054-Z57 NMT 0.20%		N.D.
	Any other impurities NMT 0.10%		0.02%
	Total impurities NMT 1.0%		0.08%
Related Substances II	SPEC054-Z19 NMT 0.30%		0.02%
	SPEC054-Z23 NMT 0.20%		0.03%
	SPEC054-Z69 NMT 0.20%		N.D.
	Total related substances I and II NMT 1.50%		0.12%
Amino Acid Analysis	Asp:0.8-1.2		1.1
	His:0.8-1.2		1.0
	Tyr: 0.8-1.2		1.2
	Lys: 0.8-1.2		1.0
	Ile: 0.8-1.2		1.0
	Aib: 0.8-1.2		0.8
	Leu: 1.6-2.4		2.2
	Val: 1.6-2.4		2.1
	Arg: 1.6-2.4		2.0
	Thr: 1.6-2.4		1.9
	Phe: 1.6-2.4		1.9
	AEEA: 1.6-2.4		1.7
	Ser: 2.4-3.6		2.8
	Ala: 2.4-3.6		3.0
	Gly: 3.2-4.8		4.0
	Glu: 4.0-6.0		5.2
	Trp (Partially destroyed during acid hydrolysis)		detected
Residual Solvents	Acetonitrile NMT 410ppm		N.D.
	Isopropyl ether NMT 5000ppm		N.D.
	Methylene chloride NMT 600ppm		N.D.
	Pyridine NMT 200ppm		N.D.
	DMF NMT 880ppm		N.D.
	TIS NMT 1000ppm		N.D.
	1,2-Ethanedithiol NMT 1000ppm		N.D.
	DIC NMT 1000ppm		N.D.
	DIEA NMT 1000ppm		N.D.
	Piperidine NMT 100ppm		N.D.
Bacterial Endotoxins	2 EU/mg		< 2 EU/mg
Microbial Limits	Total aerobic microbial count NMT 100 cfu/g		< 10 cfu/g
	Total yeasts and molds count NMT 50 cfu/g		< 10 cfu/g
	Escherichia coli count		Absent in 1g
Conclusion: This batch of product COMPLIES with the prescribed standards.
Storage condition: -20°C ± 5°C, well-closed containers, protected from light.

Main Products

How is Retatrutide different from Semaglutide and Trizepatide ?
Mechanism:
1. Semaglutide work as (GLP-1) hormone agonist.
2. Tirezepatide work as (GLP-1 & GIP ) hormone agonist.
3. Retatrutide work as (GLP-1 & GIP & Glucagon) hormones agonist.

Weight loss in trials:
1. Semaglutide led to a 6-12% reduction in body weight in 28 weeks
2. Tirezepatide led to a 15-20% reduction in body weight in 72 weeks
3. Retatrutide led to a 25% reduction in body weight in 48 weeks

Weight Management
Indicated as an adjunct to a reduced calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index (BMI) of ≥30 kg/m2 (obesity) or ≥27 kg/m2 (overweight) in the presence of at least 1 weight-related comorbid condition (eg, hypertension, type 2 diabetes mellitus, dyslipidemia)
Initiate with low dose and gradually escalate to maintenance dose of 2.4 mg/week SC to minimize GI adverse reactions
If unable to tolerate a dose during escalation, consider delaying dose escalation for 4 weeks
If unable to tolerate maintenance dose of 2.4 mg once-weekly, may temporarily decreased to 1.7 mg once weekly, for a maximum of 4 weeks; after 4 weeks, increase back to maintenance 2.4 mg once-weekly; discontinue if not tolerated after second attempt
In patients with type 2 diabetes, monitor blood glucose before initiating and during treatment
Once weekly SC dose escalation schedule:
Weeks 1-4: 0.25 mg
Weeks 5-8: 0.5 mg
Weeks 9-12: 1 mg
Week 13-16: 1.7 mg
Week 17 and onward: 2.4 mg (maintenance)

Product No.	Product
45051511	Semaglutide 5mg
45051512	Semaglutide 10mg
45051513	Semaglutide+Vitamin B12
45051514	Semaglutide+Vitamin B6
45051515	Semaglutide+L-Carnitine
45051516	Semaglutide cartridges 5mg
45051517	Semaglutide cartridges 10mg
45051518	Setmelanotide 20mg
45051519	Tirzepatide 5mg
45051520	Tirzepatide 10mg
45051521	Tirzepatide 15mg
45051522	Tirzepatide 20mg
45051523	Tirzepatide 30mg
45051524	Tirzepatide+Vitamin B12
45051525	Liraglutide 10g
45051526	Retatrutide 8mg
45051527	Retatrutide 10mg
45051528	Retatrutide 12mg
45051529	Orforglipron 1g
45051530	Mazdutide 1g
45051531	NAD+ 500mg
45051532	NAD+ 750mg
45051533	NAD+ 1000mg
45051534	NMN 150mg
45051538	Adipotide/FTPP 10mg
45051539	α-Klotho (Alpha Klotho) 50µg
45051541	A960 5mg
45051542	ARA-290 16mg
45051543	57 5mg
45051544	57 10mg
45051545	B7-33 5mg
45051546	cAC-253 (Cyclic AC-253) 10mg
45051549	DSIP 5mg
45051550	DSIP 10mg
45051551	Epitalon 10mg
45051552	Epitalon 20mg
45051553	Epitalon 100mg
45051554	FG loop (FGL) 10mg
45051556	F344 1mg
45051557	FOXO4-DRI 10mg
45051559	GHK-Cu (Copper Peptide) 50mg
45051560	GHK-Cu (Copper Peptide) 100mg
45051561	G2 10mg
45051562	G6 10mg
45051563	Gona 10mg
45051564	HC5000
45051565	Hexa 2mg
45051566	Hexa 5mg
45051568	Humanin 10mg
45051573	Ipam 5mg
45051575	Kisspeptin-10 5mg
45051576	Kisspeptin-10 10mg
45051577	KPV 5mg
45051578	KPV 10mg
45051579	LL-37 (CAP-18) 5mg
45051580	Melanotan 1 10mg
45051581	Melanotan 2 10mg
45051582	MOTS-c 5mg (acetate, TFA removed)
45051583	MOTS-c 10mg  (acetate, TFA removed)
45051584	N-Acetyl Epitalon Amidate 10mg
45051585	N-Acetyl Selank Amidate 10mg
45051586	N-Acetyl Semax Amidate 30mg
45051587	Oxytocin 10mg
45051588	PNC-27 5mg
45051590	P21 (P021) 5mg
45051591	Selank 10mg
45051592	Semax 10mg
45051593	Sermo 2mg
45051594	Sermo 5mg
45051595	SS-31 40mg
45051596	Taltirelin 10mg
45051597	Tesam 2mg
45051598	Tesam 5mg
45051600	Thymalin 20mg (63958-90-7)
45051601	Thymosin Alpha-1 3mg
45051602	Thymosin Alpha-1 5mg
45051603	Thymosin Alpha-1 10mg
45051604	Thymosinb4 5mg
45051605	Thymosinb4 10mg
45051607	TP508 Thrombin Peptide 10mg
45051608	TRH Thyrotropin (Protirelin Acetate) 20mg
45051609	VIP (Vasoactive Intestinal Peptide) 6mg
45051610	Bronchogen (Bronchi) 20mg
45051611	Cardiogen (Myocardium) 20mg
45051612	Cartalax (Joints) 20mg
45051613	Chonluten (Respiratory organs) 20mg
45051614	Cortagen (Brain) 20mg
45051615	Crystagen (Immune system) 20mg
45051616	Livagen (Liver) 20mg
45051617	Pancragen (Pancreas) 20mg
45051618	Pinealon (Brain) 20mg
45051619	Prostamax (Prostate) 20mg
45051620	Testagen (Testes) 20mg
45051621	Vesugen (Blood vessels) 20mg
45051622	Vilon (Eye retina) 20mg
45051623	B15, T50 Blend 10mg

Company Profile

ZB Bio has a long-standing track record in with successful registrations of highly purified synthetic peptide drugs of the glucagon family. Our regulatory intelligence keeps track of important changes in the relevant legislation. This enables us to be a leading global innovator in the field of glucagon and glucagon-like synthetic peptide drugs. Our services have been optimized to shorten timelines and of reduce complexity for our clients.

Our high-tech Good Manufacturing Practice (GMP) facilities based in Zhejiang province china, plus the commitment of our technical and scientific experts to quality, are the cornerstones for continuous compliance. We deliver small-scale to multi-kg active pharmaceutical ingredients (APIs) with impurities below 0.5%, identification and characterization of impurities above 0.10% using orthogonal analytical techniques.

OPTIMIZED, AUTOMATED HIGH-YIELD PRODUCTION

Our long experience in complex APIs allows us to optimize the processes for high yields at outstanding quality. Our high level of process automation allows for cost-efficient and large-scale production resulting in excellent overall material purity (>99.5%). Innovative solutions like continuous chromatography let us use equipment and resources more efficiently and help us and our partners to achieve their commitment to sustainability and environment-friendly production.

OUR TIMELINES FOR SEMAGLUTIDE

ROBUST PROCESSES AND SUPPLY SECURITY

Having our in-house building blocks for peptide synthesis as well as long-term cooperation with trusted suppliers ensures on-time production. Redundancy of multi-purpose equipment and facilities helps to mitigate risks in the supply chain, together with our stock of finished APIs and is the key for on-time product deliveries to our customers.

RELATED PRODUCTS (FOR RESEARCH PURPOSES ONLY)

Beyond GMP-grade semaglutide, we provide semaglutide in research grade, variants thereof and in different salt forms.

 

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