| CAS No.: | 52232-67-4 |
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| Formula: | C181h291n55o51s2 |
| EINECS: | 52232-67-4 |
| Type: | API |
| Appearance: | Powder |
| Quality: | Pharma Grade |
| Samples: |
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| Customization: |
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Audited Supplier Teriparatide can help make your bones stronger and reduce your risk of broken bones, especially spinal fractures.
Bones are made up of living tissue. The inside of our bones is constantly being broken down and rebuilt by specialist bone cells. As long as this process is in balance, your bones should stay healthy and strong.
But if the process becomes out of balance, our bodies can start to break down more bone than we build. This can cause the bones to become weaker and more likely to break easily.
Teriparatide can help restore the balance and make your bones stronger. It contains a hormone called parathyroid. Parathyroid hormone is made by the body to help control calcium levels in the blood. Teriparatide acts like or 'mimics' parathyroid hormone inside your bones. It works by stimulating the cells that build bone. This is different to how other osteoporosis drug treatments work.
You may still break a bone while taking teriparatide. If this happens, it doesn't necessarily mean the drug isn't working. No medication can stop all fractures, but taking teriparatide will make them much less likely.
Teriparatide isn't a pain-relieving medicine, so it won't reduce the pain caused by broken bones. But there are other treatments and ways to manage pain.
Teriparatide may be suitable if you have osteoporosis. You might be offered it as a first treatment if you have had many spinal fractures or are at a high risk of breaking another bone. This will usually be after you've already tried a different drug treatment for your bones, or if other drugs aren't suitable for you.
It is licensed for use in women who have been through the menopause, and for men. Doctors will occasionally offer it to younger women.
You will be prescribed teriparatide by a specialist at a hospital.
Teriparatide may not be suitable if you:
Teriparatide involves giving yourself an injection, just under the skin, every day.
You'll be given instructions and shown how to give yourself the injections. If you can't do them yourself, a family member or carer can do them for you. Make sure you know who to contact if you have any problems.
You can have the injection in your stomach area (abdomen) or your thigh. You can also have the injection in the outer area of your upper arm, but only if someone else does this for you.
The teriparatide injections look like a diabetic injection pen and the needle is very small. They will have already been filled with the dose of the drug you need when you get them. This type of pen should last for 28 days.
Make sure to check the instructions before you take your injection. You'll need to use a new needle for each injection. In your prescription, you may get one injection at a time or multiple packs. This may depend on the availability in your area or on the product you've been prescribed.
After you've used a needle, it should be disposed of correctly and safely. You should have a small, plastic bin with a lockable lid. If you haven't got one, ask your doctor or pharmacist for a prescription for a special sharps bin.
Teriparatide is prescribed for a maximum of two years.
It's important to try to have your injection at the same time, every day. But if you forget, take your injection as soon as you remember that same day.
If you miss the odd injection, this shouldn't affect your bone health in the long term. But try to avoid this if you can. If you often forget to take your medication, talk to your doctor.
Teriparatide needs to be stored in a fridge. How long your medication can be out of the fridge depends on the brand. Always check the information leaflet that comes with your treatment for specific information.
You'll need to use a travel bag designed to keep medication cool if you're travelling a long distance or in hot weather. It may be helpful to use cool gel packs. This will help to keep your medication at the right temperature until you have access to a fridge.
You may be able to buy a special travel bag online. You could also ask your doctor or pharmacist if the company who makes your medication provides travel bags.
You will not need to regular appointments while you're taking teriparatide. Your doctor probably won't need to see you again until your treatment finishes, unless you ask for an appointment to discuss your medication or general bone health.
Do speak to a doctor or pharmacist if you have any problems with your treatment. They may be able to suggest ways to help manage any side effects (see below). You should also contact them if you're struggling to take your injections.
If you break a bone while having teriparatide, speak to your GP. Breaking a bone doesn't necessarily mean your treatment isn't working. But it may be a good idea to have a bone health assessment.
After about two years on teriparatide, you should have a form al treatment review. Ask your doctor when this should happen if you're unsure.
You may have a bone density scan as part of your review, which will give your doctor some information about your bone strength. But they will need to consider other things as well, such as whether you've broken any bones since starting on teriparatide.
While there's no way to prove for certain that your treatment is working, research has shown that teriparatide does lower the risk of broken bones, particularly in your spine.
After your review, it's likely your doctor will advise you to start a different drug treatment.
Your doctor can advise you on what's best for you, based on your own situation.
As with any drug, teriparatide can sometimes cause side effects. The most common side effects are listed below.
It is important to remember that in general, side effects are less common than many people think. Most people on teriparatide don't have any problems. Even if you do get side effects at first, they usually improve quickly and there are ways to manage them.
For a full list of possible side effects, look at the patient information leaflet that comes with your treatment. If you don't have a copy, ask your doctor or pharmacist for one.
It's important to understand that many of these problems aren't caused by the drug. When a medicine is first tested, the people taking it have to report anything unusual to the researchers. The problems they report are often just as common in people who aren't taking the drug.
The problems listed in the table below are the main side effects that were seen more often in people taking teriparatide, rather than a dummy drug. For example, less than 1 person in every 10 people who take teriparatide will get symptoms of low mood. The other 9 in every 10 people who take the drug will not have this problem.
| Items | Specifications |
| Business Type | We are a manufacturer of GMP peptide and provide OEM service. The lid also can be customized |
| Filling amount | The filling amount is 2-5mg extra per bottle. |
| Purity | The purity is above 99% |
| Price | Competitive price |
| Delivery time | The delivery time is stable and short. If you pay before 12 a.m,the goods can be shipped on the same day. |
| Shipping risk | If the package was lost we will resend the goods to you,so you won't suffer a loss if you buy it. |
Zhaobo Bio acquired early mastery of development and manufacturing of peptides, the short chain amino acids linked by peptide bonds that have enabled new generations of small molecule drugs that closely mimic the body's natural pathways.
Now Zhaobo Bio possesses first-class capabilities to manufacture peptides at industrial scale and in full compliance with the strictest Good Manufacturing Practice (GMP) standards.
Upstream peptide synthesis
Zhaobo Bio production plants are endowed with state-of-the-art equipment for solvent supply, peptide synthesis, purification and isolation of active ingredients and intermediates. All equipment and containment is GMP qualified and cleaning validated. Overlapping capacities and sizes of different equipment trains facilitate a smooth scale-up for increases in demand within the product life cycle.
Downstream purification and isolation of peptides
Zhaobo Bio is committed to the systematic expansion and modernization of its purification equipment in order to ensure the efficient production of ever-increasing amounts of bulk peptide pharmaceuticals.
It uses sophisticated methods for large scale purification campaigns such as preparative high performance liquid chromatography (HPLC), ion exchange (IEX), size-exclusion chromatography (SEC), and ultra-filtration (UF/TFF). The equipment in place permits highly efficient or even continuous manufacturing of extremely pure products up to multi-kg quantities per lot.
For preparative HPLC, dynamic axial compression (DAC) stainless steel columns of up to 60 cm diameter both in batch and continuous mode are packed with the appropriate high performance silica separation phase. For low-pressure chromatography columns up to 80 cm diameter are available. Solvent delivery is ensured from eluent tank farms and containers.
The control of microbiological contamination is a prerequisite for API manufacturing. Class D (ISO 8) and C (ISO 7) clean rooms are supplied via HEPA-filtered, temperature and humidity controlled air, down-flow booths are used for minimizing microbial contamination and protecting operators. Highly active pharmaceutical ingredients are handled in integrated safety workbenches or flexible isolators reaching OEB level 4 (1-10 µg/m3).
Predefined physicochemical properties of the API can only be achieved by a carefully controlled isolation process. Besides precipitation and crystallization, lyophilization of intermediates and final API is a standard unit operation. LaixingPharma have multiple lyophilizers in different sizes (up to 300 liters) located in clean rooms.
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